Cabazitaxel Impurity 37 CAS CATO-C4X-111537
| CAS No. | CATO-C4X-111537 |
| Molecular Formula | C31H38O9 |
| Molecular Weight | 554.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cabazitaxel Impurity 37.
As a process- or degradation-related impurity, Cabazitaxel Impurity 37 (CAS CATO-C4X-111537, C31H38O9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Cabazitaxel Impurity 37 (C31H38O9) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 554.63 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cabazitaxel Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C31H38O9 |
| Molecular Weight | 554.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Cabazitaxel Standards
- Cabazitaxel Impurity 1 (CAS 183133-97-3)
- Cabazitaxel Impurity 3 (CAS 1444818-14-7)
- Cabazitaxel Impurity N1 (CAS 183133-94-0)
- Cabazitaxel Impurity 12 (CAS CATO-C4X-111512)
- Cabazitaxel Impurity 6 (CAS CATO-C4X-11156)
- Cabazitaxel Impurity 9 (CAS 1584118-06-8)
- Cabazitaxel Impurity N4 (CAS 1262147-55-6)
- Cabazitaxel Impurity N2 (CAS 949459-76-1)
Recommended Standards
- Benzyl 2,3-Di-O-benzyl-6-O-benzoyl-β-D-galactopyranoside (CAS 313352-43-1)
- Ubenimex Impurity 10 (CAS CATO-C4X-185210)
- Benzyl 2,3,4-Tri-O-benzyl-D-glucuronate (CAS 53684-90-5)
- Omacycline M-2 Impurity (CAS 2272886-35-6)
- Adapalene Impurity 22 (CAS CATO-C4X-180922)
- Benidipine Impurity 7 (CAS 74936-81-5)
- Mesna Impurity 6 (CAS CATO-C4X-16926)
- 5-((tert-Butoxycarbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid (CAS 914256-52-3)
- Ethyl 3-aminocinnamate 1,1-dioxide (CAS 936074-60-1)
- 5-(Chloromethyl)isoxazole-4-carboxylic acid (CAS 870704-27-1)
- (S)-1,2-Bis((benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid (CAS 816454-25-8)
- 6-(tert-Butyl)nicotinamide (CAS 4138-22-1)
- 4-(4-Chlorophenyl)-1-[(4-fluorophenyl)methyl]-2-[(E)-(phenylmethylidene)amino]-1H-pyrrole-3-carbonitrile (CAS 250713-91-8)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
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