Avanafil Impurity 111 CAS CATO-C4X-1118111

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1118111
Molecular FormulaC8H8Cl3NO
Molecular Weight240.51 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Avanafil Impurity 111 CAS CATO-C4X-1118111 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avanafil Impurity 111.

CATO supplies Avanafil Impurity 111 (CAS CATO-C4X-1118111), a pharmacopoeial impurity reference standard (molecular formula C8H8Cl3NO, MW 240.51 g/mol) used for the identification and quantification of trace impurities in APIs.

Avanafil Impurity 111 (C8H8Cl3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Avanafil Impurity 111 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H8Cl3NO
Molecular Weight240.51 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms1

Related Avanafil Standards

Recommended Standards

Why CATO?