Ivabradine Impurity 12 HCl CAS CATO-C4X-111958
| CAS No. | CATO-C4X-111958 |
| Molecular Formula | C26H34N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ivabradine Impurity 12 HCl is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ivabradine Impurity 12 HCl (CAS CATO-C4X-111958), a pharmacopoeial impurity reference standard (molecular formula C26H34N2O5HCl, MW 491.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C26H34N2O5HCl, Ivabradine Impurity 12 HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 491.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ivabradine Impurity 12 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H34N2O5 HCl |
| Molecular Weight | 491.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ivabradine Standards
- Ivabradine Impurity 25 HCl (CAS 1132079-01-6)
- Ivabradine impurity 90 (CAS 1132667-04-9)
- Ivabradine Impurity 9 (CAS 1204612-29-2)
- Ivabradine Impurity 28 (CAS 1206230-28-5)
- Ivabradine-d3 Hydrochloride (CAS 1217809-61-4)
- Ivabradine impurity 86 (CAS 1220993-44-1)
- Ivabradine Impurity 20 (CAS 1235547-06-4)
- Ivabradine Impurity 21 (CAS 1235547-07-5)
Recommended Standards
- Cholic Acid Impurity 78 (CAS 79732-73-3)
- Luliconazole impurity 30 (CAS CATO-C4X-285330)
- Tiropramide Impurity B (CAS 57227-08-4)
- 4-((6-Fluoro-2-methylquinolin-4-yl)amino)benzoic acid hydrochloride (CAS 1443279-24-0)
- tert-butyl 3-oxo-6-azabicyclo[3.1.1]heptane-6-carboxylate (CAS 1246281-86-6)
- Mithramycin A (CAS 18378-89-7)
- 3-chloro-6-methoxy-1-benzothiophene-2-carbaldehyde (CAS 725737-28-0)
- 3,5-Dichloro-4-(trifluoromethyl)benzenamine (CAS 496052-55-2)
- 4-Boc-7-bromo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine (CAS 740842-73-3)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
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