Atorvastatin Impurity 74 CAS CATO-C4X-113274
| CAS No. | CATO-C4X-113274 |
| Molecular Formula | C37H42F2N2O5 |
| Molecular Weight | 632.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Atorvastatin Impurity 74 (C37H42F2N2O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 632.74 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Atorvastatin Impurity 74 (CAS CATO-C4X-113274, C37H42F2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Atorvastatin Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H42F2N2O5 |
| Molecular Weight | 632.74 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Impurity 65 (CAS 1105067-91-1)
- Atorvastatin Impurity 79 (CAS CATO-C4X-113279)
- Atorvastatin Impurity 78 (CAS 2588261-38-3)
- Atorvastatin Pyrrolidone Analog (USP) (CAS 691844-60-7)
- Atorvastatin EP Impurity N (CAS 134395-00-9)
- Atorvastatin Impurity 69 (CAS CATO-C4X-113269)
- Atorvastatin Impurity 70 (CAS 1217751-95-5)
- Atorvastatin Impurity 71 (CAS CATO-C4X-113271)
Recommended Standards
- 2,5,8,11,14,17,20,23,26,29,32,35,38-Tridecaoxahentetracontan-41-oic acid (CAS 2170098-33-4)
- Benzonatate Impurity 1 (CAS CATO-C4X-30661)
- (OC-6-43)-Bis[2-(1H-pyrazol-1-yl-κN2)phenyl-κC][2-(2-pyridinyl-κN)phenyl-κC]iridium (CAS 858650-33-6)
- Bis(2,6-di-ter-butyl-4-methylphenyl)pentaerythritol-diphosphite (CAS 80693-00-1)
- Crizotinib Impurity 70 (CAS CATO-C4X-102570)
- Norfloxacin Impurity 63 (CAS 106847-42-1)
- Posaconazole Impurity 149 (CAS 27871-49-4)
- Auristatin E (CAS 160800-57-7)
- 2-[1-(2-Fluoroethyl)piperidin-4-yl]ethan-1-ol (CAS 1823227-90-2)
- 2-Methyl-4-nitrobenzonitrile (CAS 89001-53-6)
- (E)-Methyl 2-(2-((6-(4-chloro-2-cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylate (CAS 131860-80-5)
- Uridine Impurity 13 (CAS 1221169-70-5)
- 2-3-4-6-Tetra-O-benzoyl-β-D-glucopyranosyl isothiocyanate (CAS 132413-50-4)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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