Neratinib Impurity 55 CAS CATO-C4X-113455
| CAS No. | CATO-C4X-113455 |
| Molecular Formula | C12H11ClN2O |
| Molecular Weight | 234.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Neratinib Impurity 55.
Neratinib Impurity 55 (CAS CATO-C4X-113455) is a certified pharmaceutical impurity reference standard with the molecular formula C12H11ClN2O and a molecular weight of 234.68 g/mol.
Based on its molecular formula C12H11ClN2O, Neratinib Impurity 55 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 234.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Neratinib Impurity 55 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O |
| Molecular Weight | 234.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Neratinib Standards
- Neratinib Impurity 23 (CAS 524955-09-7)
- Neratinib Impurity 41 (CAS 1201080-20-7)
- Neratinib Impurity 58 (CAS CATO-C4X-113458)
- Neratinib Impurity 61 (CAS CATO-C4X-113461)
- Neratinib Impurity 25 (CAS 848133-87-9)
- Neratinib Impurity 51 (CAS CATO-C4X-113451)
- Neratinib Impurity 52 (CAS CATO-C4X-113452)
- Neratinib Impurity 43 (CAS 1222172-49-7)
Recommended Standards
- Clofazimine Impurity 15 (CAS CATO-C4X-207115)
- 2-(7-methoxynaphthalen-1-yl)acetyl chloride 6836-23-3 (CAS 6836-23-3)
- Monochlorobisphenol F (CAS 2148928-39-4)
- 325685-59-4 4-Chloro-6-(methoxymethyl)-2-phenylpyrimidine DTXSID60377205 (CAS 325685-59-4)
- Deflazacort Impurity 10 (CAS CATO-C4X-233610)
- Goserelin Impurity 26 Acetate (CAS 52434-75-0(free base))
- Nevirapine EP Impurity A (CAS 133627-17-5)
- 1-(2-Methoxyphenyl)-4-(naphthalen-2-ylsulfonyl)piperazine (CAS 305373-59-5)
- [1,3]Dioxolo[4,5-b]pyridin-6-ylmethanamine (CAS 1260671-81-5)
- 1,4-Thioxane (CAS 15980-15-1)
- (2-Methyl-6-(1H-pyrrol-1-yl)phenyl)methanamine (CAS 862595-58-2)
- 9-(4-(Bis(2-(acetoxymethoxy)-2-oxoethyl)amino)-3-(2-(2-(bis(2-(acetoxymethoxy)-2-oxoethyl)amino)phenoxy)ethoxy)phenyl)-3,6-bis(dimethylamino)xanthylium bromide (CAS 129787-64-0)
- 4-Ethynyl-6-fluoro-1-tosyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one (CAS 2093115-06-9)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com