Olaparib Impurity 151 CAS CATO-C4X-1135151

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1135151
Molecular FormulaC25H25FN4O3
Molecular Weight448.49 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Olaparib Impurity 151 CAS CATO-C4X-1135151 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 448.49 g/mol gives Olaparib Impurity 151 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Olaparib Impurity 151 (CAS CATO-C4X-1135151), a pharmacopoeial impurity reference standard (molecular formula C25H25FN4O3, MW 448.49 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C25H25FN4O3, Olaparib Impurity 151 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 448.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC25H25FN4O3
Molecular Weight448.49 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms4

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