Olaparib Impurity 83 CAS CATO-C4X-113583
| CAS No. | CATO-C4X-113583 |
| Molecular Formula | C24H28FN5O3 |
| Molecular Weight | 453.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Olaparib Impurity 83 (CAS CATO-C4X-113583), a pharmacopoeial impurity reference standard (molecular formula C24H28FN5O3, MW 453.51 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Olaparib Impurity 83 (C24H28FN5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H28FN5O3 |
| Molecular Weight | 453.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Olaparib Standards
- Olaparib Impurity 84 (CAS CATO-C4X-113584)
- Olaparib Impurity 161 (CAS CATO-C4X-1135161)
- Olaparib Impurity 118 (CAS CATO-C4X-1135118)
- Olaparib Impurity 160 (CAS CATO-C4X-1135160)
- Olaparib Impurity 10 (CAS CATO-C4X-113510)
- Olaparib Impurity 120 (CAS CATO-C4X-1135120)
- Olaparib Impurity 21 (CAS CATO-C4X-1135121)
- Olaparib Impurity 151 (CAS CATO-C4X-1135151)
Recommended Standards
- (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexyl)oxy]-3,5,9-trioxa-4-phosphapentadecan-1-aminium 4-oxide, inner salt 1,2-Dihexanoyl-sn-glycero-3-phosphocholine 34506-67-7 Dicaproyl-L-|A-lecithin Dihexanoyllecithin L-|A-Dihexanoyllecithin L-|A-Phosphatidylcholine, dicaproyl PC(6:0/6:0) (CAS 34506-67-7)
- N-(4-(4-Methoxyphenyl)thiazol-2-yl)-4-(2-morpholino-2-oxoethoxy)benzamide (CAS 2073059-56-8)
- Oclacitinib impurity 28 (CAS CATO-C4X-301828)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((1-(2-methoxyphenyl)-5-nitro-1H-benzo[d]imidazol-2-yl)thio)acetamide (CAS 764699-54-9)
- Tolterodine Impurity 26 (CAS 828933-86-4)
- Ticagrelor Impurity 140 (CAS CATO-C4X-1093140)
- Prostaglandin Impurity 17 (CAS 63319-59-5)
- N-(3-aminophenyl)ethanediamide (CAS 861333-02-0)
- tert-butyl 2-amino-4H,5H,7H-thieno[2,3-c]pyran-3-carboxylate (CAS 243968-52-7)
- 2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide (CAS 697770-37-9)
- 2-Thioxo-6-(p-tolyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (CAS 608491-88-9)
- Imidafenacin Related Compound 2 (CAS 503598-17-2)
- Canagliflozin Impurity 110 (CAS CATO-C4X-1123110)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com