Dapagliflozin Impurity 151 CAS CATO-C4X-1138151
| CAS No. | CATO-C4X-1138151 |
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Dapagliflozin Impurity 151 (CAS CATO-C4X-1138151, C15H14BrClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system, Dapagliflozin Impurity 151 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 10 (CAS 461432-23-5)
- Dapagliflozin Impurity 121 (CAS CATO-C4X-1138121)
- Dapagliflozin Impurity 122 (CAS CATO-C4X-1138122)
- Dapagliflozin Impurity 123 (CAS CATO-C4X-1138123)
- Dapagliflozin Impurity 141 (CAS 1629862-21-0)
- Dapagliflozin Impurity 142 (CAS CATO-C4X-1138142)
- Dapagliflozin Impurity 183 (CAS CATO-C4X-1138183)
- Dapagliflozin Impurity 198 (CAS 2454263-77-3)
Recommended Standards
- Dapagliflozin Impurity 87 (CAS CATO-C4X-113887)
- Dapagliflozin Impurity 88 (CAS CATO-C4X-113888)
- Dapagliflozin Impurity 89 (CAS CATO-C4X-113889)
- 4-(2,4-Bis(trifluoromethyl)phenyl)-2-chloropyridine (CAS 1333319-73-5)
- Ulipristal Impurity 8 (CAS 366-29-0)
- Posaconazole impurity 226 (CAS CATO-C4X-1208226)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
- 2-(3-Fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl dihydrogen phosphate (CAS 1256037-60-1)
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- 3-Ethyl-4-(4-methoxyphenyl)-4H-1,2,4-triazole (CAS 754925-60-5)
- (S)-4-Methylheptan-3-one (CAS 51532-30-0)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
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