Dapagliflozin Impurity 181 CAS CATO-C4X-1138181
| CAS No. | CATO-C4X-1138181 |
| Molecular Formula | C22H27ClO7 |
| Molecular Weight | 438.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dapagliflozin Impurity 181 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dapagliflozin Impurity 181 (CAS CATO-C4X-1138181) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27ClO7 and a molecular weight of 438.90 g/mol.
Based on its molecular formula C22H27ClO7, Dapagliflozin Impurity 181 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 438.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dapagliflozin Impurity 181 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27ClO7 |
| Molecular Weight | 438.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 119 (CAS CATO-C4X-1138119)
- Dapagliflozin Impurity 139 (CAS CATO-C4X-1138139)
- Dapagliflozin Impurity 187 (CAS CATO-C4X-1138187)
- Dapagliflozin Impurity 203 (CAS 2133407-77-7)
- Dapagliflozin Impurity 209 (CAS CATO-C4X-1138209)
- Dapagliflozin Impurity 210 (CAS CATO-C4X-1138210)
- Dapagliflozin Impurity 46 (CAS 461432-24-6)
- Dapagliflozin Impurity 65 (CAS CATO-C4X-113865)
Recommended Standards
- Canagliflozin Impurity 90 (CAS CATO-C4X-112390)
- 4-Chloro-1-trityl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (CAS 2448475-28-1)
- 2-[(2-Azidoethoxy-d4)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl)-6-methyl-1,4-dihydropyridine (CAS 1185133-69-0)
- N-Nitroso Cloxacillin Impurity 34 (CAS CATO-C4X-159734)
- Deferiprone Impurity 9 (CAS CATO-C4X-30489)
- Baloxavir Impurity 54 (CAS 2365472-39-3)
- Amorofen lmpurity 28 (CAS CATO-C4X-154228)
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- Thiazolo[5,4-d]pyrimidine-2,7-diamine (CAS 6223-69-4)
- Lefamulin Acetate (CAS 1350636-82-6)
- (6-Fluoroimidazo[1,2-a]pyridin-3-yl)(phenyl)methanone (CAS 1634647-80-5)
- 2-(Cyclopropanecarboxamido)-N-cyclopropylbenzamide (CAS 923248-61-7)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com