Omarigliptin Impurity 17 CAS CATO-C4X-114717
| CAS No. | CATO-C4X-114717 |
| Molecular Formula | C17H20F2N4O3S |
| Molecular Weight | 398.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Omarigliptin Impurity 17.
As a process- or degradation-related impurity, Omarigliptin Impurity 17 (CAS CATO-C4X-114717, C17H20F2N4O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Omarigliptin Impurity 17 (C17H20F2N4O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Omarigliptin Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20F2N4O3S |
| Molecular Weight | 398.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Omarigliptin Standards
- Omarigliptin (CAS 1226781-44-7)
- Omarigliptin Impurity 13 (CAS 1443380-88-8)
- Omarigliptin Impurity 14 (CAS CATO-C4X-114714)
- Omarigliptin Impurity 15 (CAS CATO-C4X-114715)
- Omarigliptin Impurity 18 (CAS CATO-C4X-114718)
- Omarigliptin Impurity 2 (CAS 1172623-99-2)
- Omarigliptin Impurity 3 (CAS 951127-25-6)
- Omarigliptin Impurity 4 (CAS 1456616-42-4)
Recommended Standards
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- Gefitinib Impurity 25 (CAS 385784-68-9)
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- Promethazine EP Impurity C (R-Isomer) (CAS CATO-C3D-262692)
- 6-(2-Chloro-4,5-difluorophenyl)-6-oxohexanoic acid (CAS 951891-49-9)
- 6-Morpholino-N2,N4-diphenyl-1,3,5-triazine-2,4-diamine (CAS 43167-79-9)
- tert-Butyl ((2-benzyl-2,4,5,7-tetrahydropyrano[3,4-c]pyrazol-7-yl)methyl)carbamate (CAS 1422344-07-7)
- 2-Bromo-4-chlorobenzamide (CAS 131002-01-2)
- 1-Ethyl-6-fluorobenzoimidazole (CAS 1187385-87-0)
- tert-Butyl 3-amino-4-methylpyrrolidine-1-carboxylate (CAS 889947-50-6)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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