Fosaprepitant Impurity 51 CAS CATO-C4X-116851
| CAS No. | CATO-C4X-116851 |
| Molecular Formula | C37H35F7N4O9P2 |
| Molecular Weight | 874.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Fosaprepitant Impurity 51 (CAS CATO-C4X-116851) is a certified pharmaceutical impurity reference standard with the molecular formula C37H35F7N4O9P2 and a molecular weight of 874.63 g/mol.
The molecular framework of Fosaprepitant Impurity 51 (C37H35F7N4O9P2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Fosaprepitant Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C37H35F7N4O9P2 |
| Molecular Weight | 874.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fosaprepitant Standards
- Fosaprepitant Impurity 20 (CAS CATO-C4X-116820)
- Fosaprepitant Impurity 21 (CAS 265121-01-5)
- Fosaprepitant impurity 58 (CAS CATO-C4X-116858)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 22 (CAS CATO-C4X-116822)
- Fosaprepitant Impurity 42 (CAS CATO-C4X-116842)
- Fosaprepitant Impurity 44 (CAS CATO-C4X-116844)
- Fosaprepitant Impurity 45 (CAS CATO-C4X-116845)
Recommended Standards
- [1,3-Bis(2,4,6-trimethylphenylimidazolidin-2-ylidene)(tricyclohexylphosphine)-(2-oxo-5-nitrobenzylidene)ruthenium(II) (CAS 1544328-53-1)
- Thonningianin A (CAS 271579-11-4)
- 1,2-dihenarachidoyl-sn-glycero-3-phosphocholine 253685-28-8 (CAS 253685-28-8)
- [(1R)-[1,1'-Binaphthalene]-2,2'-diylbis(3-methyl-1H-benzimidazol-1-yl-2(3H)-ylidene)]palladium diiode (CAS 930093-61-1)
- Famciclovir Impurity 3 (CAS CATO-C4X-16423)
- Promethazine Impurity 8 (CAS CATO-C4X-14188)
- Acetylcysteine Impurity 20 (CAS CATO-C4X-153220)
- 1-(1H-Pyrrolo[2,3-b]pyridin-6-yl)ethan-1-amine (CAS 2090754-68-8)
- 2-[(2-Chloro-6-fluorophenyl)methyl]-4-[(1E)-{[(4-methylphenyl)methyl]imino}methyl]benzene-1,3-diol (CAS 341967-46-2)
- 5-((1H-pyrrol-2-yl)methyl)-1H-pyrrole-2-carbaldehyde (CAS 36746-27-7)
- 9a-(4-Fluorophenyl)-octahydro-1H-pyrrolo[1,2-a][1,3]diazepin-7-one (CAS 1148027-29-5)
- 4-(4-Bromophenyl)piperidine-4-carboxylic acid (CAS 913542-80-0)
- 5-(2-hydroxyethyl)-1,2-dihydropyrimidin-2-one hydrochloride (CAS 1803571-24-5)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com