Hydrochlorothiazide Impurity 43 CAS CATO-C4X-117743
| CAS No. | CATO-C4X-117743 |
| Molecular Formula | C6H5Cl2NO5S2 |
| Molecular Weight | 306.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Hydrochlorothiazide Impurity 43 (CAS CATO-C4X-117743), a pharmacopoeial impurity reference standard (molecular formula C6H5Cl2NO5S2, MW 306.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution, Hydrochlorothiazide Impurity 43 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 306.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5Cl2NO5S2 |
| Molecular Weight | 306.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide Impurity 42 (CAS CATO-C4X-117742)
- Hydrochlorothiazide-13C6 (CAS 1261396-79-5)
- Hydrochlorothiazide-15N2-13C-d2 (CAS 2140316-81-8)
- Hydrochlorothiazide Impurity 24 (CAS 1025-75-8)
- Hydrochlorothiazide Impurity 32 (CAS CATO-C4X-117732)
- Hydrochlorothiazide Impurity 33 (CAS CATO-C4X-117733)
- Hydrochlorothiazide-13C,d2 (CAS 1190006-03-1)
- Hydrochlorothiazide Impurity 18 (CAS 89813-56-9)
Recommended Standards
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- Tertiapin-Q (CAS 910044-56-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com