Eltrombopag Impurity 111 CAS CATO-C4X-1198111
| CAS No. | CATO-C4X-1198111 |
| Molecular Formula | C14H11NO5 |
| Molecular Weight | 273.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H11NO5, Eltrombopag Impurity 111 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 273.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Eltrombopag Impurity 111 (CAS CATO-C4X-1198111) is a certified pharmaceutical impurity reference standard with the molecular formula C14H11NO5 and a molecular weight of 273.24 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Eltrombopag Impurity 111 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11NO5 |
| Molecular Weight | 273.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 109 (CAS CATO-C4X-1198109)
- Eltrombopag Impurity 110 (CAS CATO-C4X-1198110)
- Eltrombopag Impurity 112 (CAS CATO-C4X-1198112)
- Eltrombopag Impurity 125 (CAS CATO-C4X-1198125)
- Eltrombopag Impurity 126 (CAS CATO-C4X-1198126)
- Eltrombopag impurity 140 (CAS CATO-C4X-1198140)
- Eltrombopag Impurity 20 (CAS 376591-94-5)
- Eltrombopag Impurity 56 (CAS 36324-64-8)
Recommended Standards
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