Sorafenib Impurity 56 CAS 864272-34-4
| CAS No. | 864272-34-4 |
| Molecular Formula | C13H11N3O4 |
| Molecular Weight | 273.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sorafenib Impurity 56 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Sorafenib Impurity 56 (CAS 864272-34-4), a pharmacopoeial impurity reference standard (molecular formula C13H11N3O4, MW 273.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Sorafenib Impurity 56 (C13H11N3O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 273.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H11N3O4 |
| Molecular Weight | 273.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related Sorafenib Standards
- Sorafenib EP Impurity B (CAS 2004659-84-9)
- Sorafenib EP Impurity G (CAS 18585-06-3)
- Sorafenib Impurity 11 (CAS 1129683-88-0)
- Sorafenib Impurity 60 (CAS 284462-86-8)
- Sorafenib Impurity 29 (CAS CATO-C4X-112429)
- Sorafenib impurity 65 (CAS CATO-C4X-112465)
- Sorafenib Impurity 27 (CAS 757251-59-5)
- Sorafenib impurity 64 (CAS CATO-C4X-112464)
Recommended Standards
- 4-Amino-2-nitrodiphenylamine-2'-carboxylic acid (CAS 117907-43-4)
- Eltrombopag Impurity 109 (CAS CATO-C4X-1198109)
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- Eltrombopag Impurity 110 (CAS CATO-C4X-1198110)
- Rivaroxaban Impurity 134 (CAS 36157-41-2)
- Lenalidomide Impurity 25 (CAS 1218910-61-2)
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- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-3-(trifluoromethyl)benzamide (CAS 477866-74-3)
- N-(4-Methoxybenzyl)oxetan-3-amine (CAS 1344099-05-3)
- (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-ethoxy-6-quinazolinyl]-4-(dimethylamino)-2-butenamide (CAS 2085843-51-0)
- Bedaquiline impurity 69 (CAS CATO-C4X-116769)
- 4-(2-Chlorobenzoyl)isoquinoline (CAS 1187169-58-9)
- 3-(2-Naphthyl)-1-phenylpyrazole-4-carbaldehyde (CAS 36640-53-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com