Eltrombopag impurity 150 CAS CATO-C4X-1198150
| CAS No. | CATO-C4X-1198150 |
| Molecular Formula | C17H16N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Eltrombopag impurity 150 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Eltrombopag impurity 150 (CAS CATO-C4X-1198150) is a certified pharmaceutical impurity reference standard with the molecular formula C17H16N4O6Na and a molecular weight of 395.33 g/mol.
Eltrombopag impurity 150 (C17H16N4O6Na) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H16N4O6 2*Na |
| Molecular Weight | 395.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Eltrombopag Standards
- Eltrombopag Impurity 39 (CAS 103966-66-1)
- Eltrombopag Impurity 89 (CAS 1097777-60-0)
- Eltrombopag Impurity 94 (CAS 1176777-76-6)
- Eltrombopag Impurity 102 (CAS 118048-94-5)
- Eltrombopag-13C4 (CAS 1217230-31-3)
- Eltrombopag Methyl Ester (CAS 1246929-01-0)
- Eltrombopag Impurity 4 (CAS 1246929-02-1)
- Eltrombopag Impurity 34 (CAS 13073-25-1)
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