Posaconazole Impurity 98 CAS CATO-C4X-120898
| CAS No. | CATO-C4X-120898 |
| Molecular Formula | C14H16F2O3 |
| Molecular Weight | 270.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Posaconazole Impurity 98 (C14H16F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Posaconazole Impurity 98 (CAS CATO-C4X-120898) is a certified pharmaceutical impurity reference standard with the molecular formula C14H16F2O3 and a molecular weight of 270.27 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Posaconazole Impurity 98 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H16F2O3 |
| Molecular Weight | 270.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Posaconazole Standards
- Posaconazole Impurity 80 (CAS CATO-C4X-1208180)
- Posaconazole Impurity 81 (CAS CATO-C4X-1208181)
- Posaconazole Impurity 77 (CAS 74853-08-0)
- Posaconazole Impurity 90 (CAS CATO-C4X-1208190)
- Posaconazole Impurity 91 (CAS CATO-C4X-1208191)
- Posaconazole Impurity 35 (CAS 1370190-85-4)
- Posaconazole Impurity 132 (CAS CATO-C4X-1208132)
- Posaconazole Impurity 270 (CAS 55743-71-0)
Recommended Standards
- Tedizolid Impurity 29 (CAS 1638760-07-2)
- Isavuconazole impurity 66 (CAS CATO-C4X-1236166)
- 898752-26-6 Ethyl 6-(3,4-difluorophenyl)-6-oxohexanoate DTXSID50645581 (CAS 898752-26-6)
- Efinaconazole Impurity 35 (CAS 127001-03-0)
- Lumateperone Impurity 19 (CAS CATO-C4X-220119)
- Xanomeline impurity 26 (CAS CATO-C4X-330126)
- Ziprasidone Impurity 2 (CAS 684269-12-3)
- 1-(Dimethylamino)cyclopropanecarbaldehyde (CAS 1229114-92-4)
- 2-(1-((Benzyloxy)carbonyl)-3-fluoropiperidin-4-yl)acetic acid (CAS 1373503-25-3)
- 2-(cyclohexylmethoxy)-4,6-dimethylpyridine-3-carboxylic acid (CAS 1455433-22-3)
- tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazol-2-yl)carbamate (CAS 1392846-50-2)
- 3-Bromo-2-chloro-6-iodopyridine (CAS 1260666-58-7)
- Vericiguat Impurity 87 (CAS CATO-C4X-289687)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
Why CATO?
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