Dorzolamide Impurity 18 Disodium Salt (Mixture of Diastereomers) CAS CATO-C4X-122818
| CAS No. | CATO-C4X-122818 |
| Molecular Formula | C14H19N2O8S3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Dorzolamide Impurity 18 Disodium Salt (Mixture of Diastereomers) (CAS CATO-C4X-122818, C14H19N2O8S3Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Dorzolamide Impurity 18 Disodium Salt (Mixture of Diastereomers) (C14H19N2O8S3Na) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Dorzolamide Impurity 18 Disodium Salt (Mixture of Diastereomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19N2O8S3 2*Na |
| Molecular Weight | 462.48 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Dorzolamide Standards
- Dorzolamide Impurity 8 (CAS 120279-26-7)
- Dorzolamide EP Impurity A HCl (CAS 120279-36-9)
- Dorzolamide EP Impurity B HCl (CAS 120279-37-0)
- Dorzolamide EP Impurity A (CAS 120279-95-0)
- Dorzolamide (CAS 120279-96-1)
- Rac-Dorzolamide (CAS 120280-13-9)
- Dorzolamide EP Impurity A HCl (CAS 122028-36-8)
- Dorzolamide-d5 (CAS 1227097-70-2)
Recommended Standards
- Exemestane Impurity 28 (CAS CATO-C4X-164128)
- Nadifloxacin Impurity 7 (CAS CATO-C4X-21117)
- Dalbavancin Impurity 29 (CAS CATO-C4X-160229)
- rac-Tamsulosin EP Impurity H HCl (CAS 2724727-12-0)
- Tiotropium Impurity 27 (CAS 3140-93-0)
- Ethyl 2-(3-aminophenyl)-4-methylthiazole-5-carboxylate (CAS 209538-96-5)
- (R)-2-(4-(tert-Butyl)benzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1049728-56-4)
- Ethyl 4-methoxypyrimidine-5-carboxylate (CAS 71133-21-6)
- 2-Phenylthiophene (CAS 825-55-8)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
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