Isavuconazole Impurity 131 Iodization HCl (Mixture of Diastereomers) CAS CATO-C4X-1236131
| CAS No. | CATO-C4X-1236131 |
| Molecular Formula | C35H35F2N8O5S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Isavuconazole Impurity 131 Iodization HCl (Mixture of Diastereomers) (CAS CATO-C4X-1236131, C35H35F2N8O5SIHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Isavuconazole Impurity 131 Iodization HCl (Mixture of Diastereomers) (C35H35F2N8O5SIHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C35H35F2N8O5S I HCl |
| Molecular Weight | 881.13 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Tetracaine impurity 20 (CAS 1152620-27-3)
- Articaine Impurity C7 (CAS 23964-64-9)
- Sugammadex Impurity 50 (CAS 2379877-88-8)
- [(N-Benzyl-N-methylammonium)methyl]trifluoroborate internal salt (CAS 1268341-00-9)
- 2-Bromo-7-chloro-3,4-dihydronaphthalen-1(2H)-one (CAS 56820-57-6)
- tert-Butyl 4-bromo-3-(hydroxymethyl)-1H-indole-1-carboxylate (CAS 914349-05-6)
- 3-Bromo-4-methoxycinnamic acid (CAS 1080-07-5)
- ITI-214, >98% (HPLC) (CAS 1642303-38-5)
- 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide 349085-38-7 HC 030031 HC-030031 (CAS 349085-38-7)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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