Isavuconazole Impurity 135 CAS CATO-C4X-1236135
| CAS No. | CATO-C4X-1236135 |
| Molecular Formula | C30H33F2N6O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Isavuconazole Impurity 135 (CAS CATO-C4X-1236135, C30H33F2N6O3SI) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Isavuconazole Impurity 135 (C30H33F2N6O3SI) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Isavuconazole Impurity 135 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H33F2N6O3S I |
| Molecular Weight | 722.59 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Apalutamide Impurity 51 (CAS CATO-C4X-274951)
- Solriamfetol Impurity 30 (CAS CATO-C4X-256330)
- Cefuroxime Impurity 48 (CAS CATO-C4X-124548)
- 3-(Methoxymethyl)isonicotinic acid (CAS 1192021-83-2)
- (R)-4-(1-Aminoethyl)phenol hydrochloride (CAS 2061996-43-6)
- n-(2-Methoxyphenyl)piperidine-4-carboxamide hydrochloride (CAS 1019851-99-0)
- 2-((1-((Diethylamino)methyl)-1H-1,2,4-triazol-5-yl)thio)acetonitrile (CAS 61691-07-4)
- 1,2-Dibromo-1,1-dichloroethane (CAS 75-81-0)
- N-(3-Isobutoxybenzyl)-4-isopropoxyaniline (CAS 1040692-88-3)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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