Ixazomib Impurity 16 CAS CATO-C4X-126716
| CAS No. | CATO-C4X-126716 |
| Molecular Formula | C14H18BCl3N2O4 |
| Molecular Weight | 395.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ixazomib Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Ixazomib Impurity 16 (CAS CATO-C4X-126716), a pharmacopoeial impurity reference standard (molecular formula C14H18BCl3N2O4, MW 395.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ixazomib Impurity 16 (C14H18BCl3N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 395.47 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H18BCl3N2O4 |
| Molecular Weight | 395.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ixazomib Standards
- Ixazomib Impurity 17 (CAS CATO-C4X-126717)
- Ixazomib Impurity 18 (CAS CATO-C4X-126718)
- Ixazomib Impurity 44 (CAS CATO-C4X-126744)
- Ixazomib-13C2,15N (CAS CATO-C4X-126764)
- Ixazomib Impurity 81 (CAS CATO-C4X-126781)
- Ixazomib (CAS 1072833-77-2)
- Ixazomib Impurity 3 (CAS CATO-C4X-12673)
- Ixazomib Impurity 77 (CAS CATO-C4X-126777)
Recommended Standards
- Etoricoxib Impurity 93 (CAS CATO-C4X-108093)
- Etoricoxib Impurity 89 (CAS CATO-C4X-108089)
- Spiperone (CAS 749-02-0)
- Cabozantinib Impurity 14 (CAS CATO-C4X-201814)
- Dexpanthenol Impurity 12 (CAS 13031-04-4)
- Amoxicillin Impurity 101 (CAS CATO-C4X-1148101)
- Ornidazole impurity 33 (CAS CATO-C4X-133133)
- 4-Phenethyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide (CAS 120991-35-7)
- [(3,4-Dimethoxyphenyl)methyl](prop-2-en-1-yl)amine hydrochloride (CAS 1158740-54-5)
- (2,4-Dibromo-3-(difluoromethoxy)phenyl)methanol (CAS 1804514-71-3)
- 1-(3-Chlorophenyl)-2-(isopropylamino)ethan-1-ol (CAS 23299-18-5)
- 2-Methyl-6-(pyridin-3-yl)imidazo[2,1-b]thiazole (CAS 96911-77-2)
- 4-Methanesulfonyl-2-(trifluoromethyl)benzoic acid (CAS 118939-17-6)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
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