Bendamustine Impurity 20 CAS CATO-C4X-127120
| CAS No. | CATO-C4X-127120 |
| Molecular Formula | C19H27Cl2N3O4 |
| Molecular Weight | 432.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Bendamustine Impurity 20 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Bendamustine Impurity 20 (CAS CATO-C4X-127120, C19H27Cl2N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bendamustine Impurity 20 (C19H27Cl2N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Bendamustine Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H27Cl2N3O4 |
| Molecular Weight | 432.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Bendamustine Standards
- Bendamustine Impurity 19 (CAS CATO-C4X-127119)
- Bendamustine impurity 32 (CAS CATO-C4X-127132)
- Bendamustine USP Related Compound I (CAS 87475-54-5)
- Bendamustine Impurity 14 (CAS CATO-C4X-127114)
- Bendamustine Impurity 15 (CAS CATO-C4X-127115)
- Bendamustine Impurity 18 (CAS CATO-C4X-127118)
- Bendamustine Impurity 31 (CAS CATO-C4X-127131)
- Bendamustine impurity 43 (CAS CATO-C4X-127143)
Recommended Standards
- Ozenoxacin Impurity 37 (CAS CATO-C4X-279637)
- N-(4-Bromo-2-methylphenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573973-11-2)
- (3-Nitro-4-phenoxyphenyl)methyl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338960-92-2)
- N-(4-Bromo-2-methylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 578744-30-6)
- Sucralfate EP Impurity A Octasodium Salt (CAS 74135-10-7)
- Rosuvastatin Impurity 78 (CAS 488798-37-4)
- Sulindac EP Impurity C-d3 (CAS 250608-66-3)
- 2-Fluoro-4,6-dimethylpyrimidine (CAS 38953-33-2)
- 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoic acid (CAS 1870019-79-6)
- 22(R)-hydroxycholesterol-d7 (CAS 1246302-93-1)
- Besudil Impurity 7 (CAS CATO-C4X-29887)
- Ethyl 3-amino-4-cyano-1-methyl-1H-pyrrole-2-carboxylate (CAS 145162-36-3)
- (S)-3,3-Bis[3,5-bis(trifluoromethyl)phenyl]-1,1-binaphthyl-2,2-diyl-N-triflyl phosphoramide (CAS 1836233-61-4)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com