Retigabine impurity 18 CAS CATO-C4X-13158
| CAS No. | CATO-C4X-13158 |
| Molecular Formula | C32H34F2N6O4 |
| Molecular Weight | 604.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Retigabine impurity 18.
As a process- or degradation-related impurity, Retigabine impurity 18 (CAS CATO-C4X-13158, C32H34F2N6O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Retigabine impurity 18 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 604.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Retigabine impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H34F2N6O4 |
| Molecular Weight | 604.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Retigabine Standards
- Retigabine impurity 17 (CAS CATO-C4X-13157)
- Retigabine 3,3'-Dimer (CAS 1588430-16-3)
- Retigabine N-β-D-Glucuronide Sodium Salt (CAS 191873-41-3)
- Retigabine Impurity 4 (CAS 914219-00-4)
- Retigabine impurity 16 (CAS CATO-C4X-13156)
- Retigabine Impurity 2 (CAS CATO-C4X-13142)
- Retigabine Impurity 3 (CAS 1263404-73-4)
- Retigabine impurity 11 (CAS CATO-C4X-13151)
Recommended Standards
- Fmoc-D-Asp(OtBu)-(Hmb)Gly-OH (CAS 1926163-00-9)
- Posaconazole Impurity 167 (CAS CATO-C4X-1208167)
- N1,N2-Bis((2-(diphenylphosphino)phenyl)methylene)-1,2-ethanediamine (CAS 74684-87-0)
- 4-Methoxyphenyl (1S,2S)-2-((R)-4-((9H-xanthen-9-yl)methyl)-1-(4-methoxybenzyl)-2,5-dioxoimidazolidin-4-yl)cyclopropane-1-carboxylate (CAS 201851-12-9)
- Dotinurad Impurity 91 (CAS CATO-C4X-249491)
- Progesterone EP Impurity I (CAS 24254-01-1)
- Melphalan EP Impurity K (CAS 109-89-7)
- (2-Chlorophenyl)(1H-imidazol-2-yl)methanone (CAS 287196-66-1)
- (E)-1-butyl-2-((2-fluorobenzylidene)amino)-4,5-diphenyl-1H-pyrrole-3-carbonitrile (CAS 478032-72-3)
- 3-Amino-1,1-dioxo-thietane-3-carbonitrilehydrochloride (CAS 2306268-09-5)
- 3,6-Dihydro-3-methyl-N-nitro-2H-1,3,5-oxadiazin-4-amine (CAS 153719-38-1)
- (3S,4S)-4-((tert-butoxycarbonyl)amino)-3-hydroxycyclopent-1-ene-1-carboxylic acid (CAS 2387568-31-0)
- N-((1H-Imidazol-4-yl)methyl)-N-hydroxybenzamide (CAS 61548-89-8)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com