Retigabine impurity 11 CAS CATO-C4X-13151
| CAS No. | CATO-C4X-13151 |
| Molecular Formula | C19H22FN3O4 |
| Molecular Weight | 375.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Retigabine impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Retigabine impurity 11 (CAS CATO-C4X-13151) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22FN3O4 and a molecular weight of 375.39 g/mol.
Retigabine impurity 11 (C19H22FN3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H22FN3O4 |
| Molecular Weight | 375.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Retigabine Standards
- Retigabine Impurity 2 (CAS CATO-C4X-13142)
- Retigabine Impurity 3 (CAS 1263404-73-4)
- Retigabine impurity 16 (CAS CATO-C4X-13156)
- Retigabine impurity 13 (CAS CATO-C4X-13153)
- Retigabine (CAS 150812-12-7)
- Retigabine Impurity 1 (CAS CATO-C4X-13141)
- Retigabine impurity 8 (CAS CATO-C4X-13148)
- Retigabine impurity 9 (CAS CATO-C4X-13149)
Recommended Standards
- Levofloxacin Impurity 40 (CAS 106939-30-4)
- Levofloxacin Methyl Ester (CAS 862690-19-5)
- Gatifloxacin USP RC E (CAS 1029364-65-5)
- Levofloxacin impurity 78 (CAS 107359-24-0)
- Lidocaine impurity 66 (CAS CATO-C4X-167966)
- Estriol Impurity 19 (CAS CATO-C4X-163719)
- Tenofovir Alafenamide Impurity 27 HCl (CAS 431949-21-2(Free))
- (2-Oxa-5-azabicyclo[2.2.1]Heptan-4-yl)methanol (CAS 2169602-18-8)
- 9-Hexyl-3,6-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 628336-95-8)
- 2-(4-Methylthiazol-5-yl)ethyl octanoate (CAS 163266-17-9)
- 7a-Phenyl-hexahydro-1H-pyrrolo[1,2-a]imidazol-5-one (CAS 7421-62-7)
- 3-Chloro-5-(methylthio)-1,2,4-triazine (CAS 1247802-89-6)
- 3-chloronaphthalene-1-carboxylic acid (CAS 5774-06-1)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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