Retigabine Impurity 4 CAS 914219-00-4
| CAS No. | 914219-00-4 |
| Molecular Formula | C22H26FN3O6 |
| Molecular Weight | 447.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 447.46 g/mol gives Retigabine Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Retigabine Impurity 4 (CAS 914219-00-4) is a certified pharmaceutical impurity reference standard with the molecular formula C22H26FN3O6 and a molecular weight of 447.46 g/mol.
Structurally, Retigabine Impurity 4 (C22H26FN3O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 447.46 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Retigabine Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H26FN3O6 |
| Molecular Weight | 447.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Retigabine Standards
- Retigabine N-β-D-Glucuronide Sodium Salt (CAS 191873-41-3)
- Retigabine impurity 16 (CAS CATO-C4X-13156)
- Retigabine Impurity 2 (CAS CATO-C4X-13142)
- Retigabine Impurity 3 (CAS 1263404-73-4)
- Retigabine impurity 11 (CAS CATO-C4X-13151)
- Retigabine impurity 13 (CAS CATO-C4X-13153)
- Retigabine (CAS 150812-12-7)
- Retigabine Impurity 1 (CAS CATO-C4X-13141)
Recommended Standards
- Gatifloxacin impurity 31 (CAS CATO-C4X-125331)
- Levofloxacin Impurity 42 (CAS 1330277-19-4)
- N-(4-(N-(2-Benzoylphenyl)sulfamoyl)phenyl)oxazole-5-carboxamide (CAS 827577-66-2)
- relugolix Impurity 93 (CAS CATO-C4X-242993)
- Amphotericin B EP Impurity B (CAS 136135-57-4)
- Tinidazole Impurity 24 (CAS CATO-C4X-193024)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
- 2-(3,4-Dipropoxybenzoyl)benzoic acid (CAS 556007-01-3)
- 2-(1-Methylpyrrolidin-3-yl)propan-2-ol (CAS 412283-55-7)
- (S)-5-Amino-7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 167888-21-3)
- 3-(Bromomethyl)-4-fluorobenzaldehyde (CAS 1379371-56-8)
- N-(4-Ethoxyphenyl)-2-((1-(2-methylbenzyl)-1H-indol-3-yl)sulfonyl)acetamide (CAS 850932-85-3)
- 1-(Piperidin-4-ylsulfonyl)piperidine hydrochloride (CAS 2138171-83-0)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
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