Nafamostat impurity 83 CAS CATO-C4X-133283
| CAS No. | CATO-C4X-133283 |
| Molecular Formula | C18H15N3O2 |
| Molecular Weight | 305.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 305.33 g/mol gives Nafamostat impurity 83 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nafamostat impurity 83 (CAS CATO-C4X-133283) is a certified pharmaceutical impurity reference standard with the molecular formula C18H15N3O2 and a molecular weight of 305.33 g/mol.
Structurally, Nafamostat impurity 83 (C18H15N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 305.33 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15N3O2 |
| Molecular Weight | 305.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Nafamostat Standards
- Nafamostat impurity 82 (CAS CATO-C4X-133282)
- Nafamostat impurity 84 (CAS 82955-97-3)
- Nafamostat Impurity 128 (CAS CATO-C4X-1332128)
- Nafamostat Impurity 53 (CAS CATO-C4X-133253)
- Nafamostat impurity 73 (CAS CATO-C4X-133273)
- Nafamostat impurity 130 (CAS CATO-C4X-1332130)
- Nafamostat impurity 115 (CAS CATO-C4X-1332115)
- Nafamostat Impurity N3 (CAS 115325-88-7)
Recommended Standards
- Dobutamine Impurity 47 (CAS CATO-C4X-129847)
- Enalapril Impurity 13 (CAS 84793-24-8)
- Bendamustine Impurity 25 (CAS 3543-76-8)
- Docetaxel Impurity 22 (CAS 161183-22-8)
- Colchicine Impurity 8 (CAS 6877-25-4)
- Brivaracetam Impurity 69 (CAS CATO-C4X-200769)
- Rasagiline impurity 56 (CAS CATO-C4X-191356)
- n-Benzyl-4-bromo-3-methylbenzenesulfonamide (CAS 1003740-81-5)
- Tert-butyl (R)-3,3-difluoro-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 2199215-19-3)
- 2,7-Diaminofluorene Dihydrochloride (CAS 13548-69-1)
- Cyclohexyl(3-fluorophenyl)methanone (CAS 898769-09-0)
- 3-[(2S)-Oxiran-2-yl]pyridine (CAS 329281-07-4)
- Pheniramine (CAS 86-21-5)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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