Umeclidinium Impurity 17 CAS CATO-C4X-133917
| CAS No. | CATO-C4X-133917 |
| Molecular Formula | C23H28NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Umeclidinium Impurity 17 (CAS CATO-C4X-133917), a pharmacopoeial impurity reference standard (molecular formula C23H28NO2Br, MW 430.39 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Umeclidinium Impurity 17 (C23H28NO2Br) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H28NO2 Br |
| Molecular Weight | 430.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Umeclidinium Standards
- Umeclidinium Bromide Impurity 25 (CAS 119102-52-2)
- Umeclidinium impurity 26 (CAS 1248400-28-3)
- Umeclidinium Impurity 1 (CAS 1509910-91-1)
- Umeclidinium impurity 22 (CAS 17229-17-3)
- Umeclidinium Impurity 15 (CAS 2230024-91-4(free base))
- Umeclidinium Impurity 19 (CAS 2253743-32-5)
- Umeclidinium Impurity 13 (CAS 2253743-36-9)
- Umeclidinium Impurity 11 (CAS 2253743-38-1)
Recommended Standards
- Erlotinib Impurity 12 (CAS 183322-20-5)
- Resmetirom Impurity 25 (CAS CATO-C4X-291225)
- Linagliptin Impurity 80 (CAS 2446799-71-7)
- Ethyl imidazo[1,2-a]pyridine-2-carboxylate hydrobromide (CAS 2549-17-9)
- [3,3'-Bipyridin]-2-amine (CAS 163563-02-8)
- 2-Fluoro-N-(thiophen-3-ylmethyl)aniline (CAS 1019604-91-1)
- ((4R,5R)-2-Isopropyl-1,3-dioxolane-4,5-diyl)dimethanamine (CAS 146092-05-9)
- 1-(2-Amino-4,5-dimethoxyphenyl)-2-phenylethan-1-one (CAS 85636-82-4)
- (1R,3r,5S)-Spiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolan]-3-ol (CAS 91036-42-9)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com