Sertraline Impurity 59 CAS CATO-C4X-134459
| CAS No. | CATO-C4X-134459 |
| Molecular Formula | C17H18ClN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 308.25 g/mol gives Sertraline Impurity 59 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Sertraline Impurity 59 (CAS CATO-C4X-134459) is a certified pharmaceutical impurity reference standard with the molecular formula C17H18ClNHCl and a molecular weight of 308.25 g/mol.
The molecular framework of Sertraline Impurity 59 (C17H18ClNHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18ClN HCl |
| Molecular Weight | 308.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline Acetamide (CAS 1097616-52-8)
- Sertraline Carbamoyl Glucuronide (CAS 119733-44-7)
- Sertraline Impurity 26 (CAS 1198115-10-4（free base）)
- Sertraline RC 11 (CAS 1217630-23-3)
- Sertraline-d3 Hydrochloride (CAS 1217741-83-7)
- Sertraline Impurity 50 HCl (CAS 122873-20-5 (free base))
- Sertraline EP Impurity F Enantiomer (CAS 124379-29-9)
Recommended Standards
- Bilastine Impurity 65 (CAS CATO-C4X-225365)
- Orforglipron Impurity 146 (CAS CATO-C4X-3234146)
- LCZ-696 Impurity 22 (CAS 149709-59-1)
- 2-(((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methyl)thio)-5,6,7,8-tetrahydroquinazolin-4(3H)-one (CAS 1040635-48-0)
- N-Allyl-N-(5-phenylfuran-2-yl)heptanamide (CAS 62187-65-9)
- 3-[(2-Bromoacetyl)amino]-N-(tetrahydro-2-furanylmethyl)benzamide (CAS 1138442-86-0)
- Posaconazole Impurity 157 (CAS CATO-C4X-1208157)
- N6-Benzoyl-3-O-tert-butyldimethylsilyl-5-O-DMT-adenosine 2-CE phosphoramidite (CAS 129451-75-8)
- Baloxavir Impurity 144 (CAS CATO-C4X-2108144)
- Angiotensin II Antipeptide (CAS 121379-63-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com