Flunarizine Impurity 58 CAS CATO-C4X-135758
| CAS No. | CATO-C4X-135758 |
| Molecular Formula | C27H18F4O3 |
| Molecular Weight | 466.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 466.42 g/mol gives Flunarizine Impurity 58 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Flunarizine Impurity 58 (CAS CATO-C4X-135758, C27H18F4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution, Flunarizine Impurity 58 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H18F4O3 |
| Molecular Weight | 466.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Flunarizine Standards
- Flunarizine impurity 51 (CAS CATO-C4X-135751)
- Flunarizine Impurity 14 (CAS CATO-C4X-135714)
- Flunarizine Impurity 15 (CAS CATO-C4X-135715)
- Flunarizine impurity 53 (CAS CATO-C4X-135753)
- Flunarizine Impurity 7 (CAS 87166-81-2)
- Flunarizine Impurity N1 (CAS 123375-94-0)
- Flunarizine impurity 34 (CAS CATO-C4X-135734)
- Flunarizine impurity 39 (CAS 19422-37-8)
Recommended Standards
- N-(2-Bromo-4-methylphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-73-9)
- 1-(3-(Trifluoromethyl)phenoxy)-3-(triphenyl-l5-phosphanylidene)propan-2-one (CAS 73718-90-8)
- 2-(1-(7-(4-Bromo-2,6-dimethylphenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl)acetonitrile (CAS 724475-37-0)
- Salicyl-AMS (CAS 863238-55-5)
- Tenofovir Alafenamide 64 (CAS CATO-C4X-179764)
- Sulpiride EP Impurity B (CAS 33045-52-2)
- Verapamil Impurity 51 (CAS CATO-C4X-177851)
- Ethyl 4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1638768-98-5)
- Rivaroxaban Impurity 135 (CAS 53935-71-0)
- 2,2,2-Trifluoro-1-(4-(6-(p-tolyl)pyridazin-3-yl)piperazin-1-yl)ethan-1-one (CAS 1021070-05-2)
- 4-{8-methyl-8H-thieno[2,3-b]indole-2-carbonyl}morpholine (CAS 172869-39-5)
- Atropine Impurity 46 (CAS 1690-22-8)
- 4-(4-(Dimethylamino)phenyl)thiazol-2-amine (CAS 874816-07-6)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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