S-Adenosyl-L-Methionine Impurity 21 CAS CATO-C4X-138121

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-138121
Molecular Formula-
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

S-Adenosyl-L-Methionine Impurity 21 CAS CATO-C4X-138121 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including S-Adenosyl-L-Methionine Impurity 21.

CATO supplies S-Adenosyl-L-Methionine Impurity 21 (CAS CATO-C4X-138121), a pharmacopoeial impurity reference standard (molecular formula C15H20D3N6O5SH2O4SHO4S, MW 597.60 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of S-Adenosyl-L-Methionine Impurity 21 (C15H20D3N6O5SH2O4SHO4S) is characterized by deuterium isotope labeling, a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), S-Adenosyl-L-Methionine Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H20D3N6O5S H2O4S HO4S
Molecular Weight597.60 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms6
Sulfur Atoms3

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