Furosemide Impurity 11 CAS CATO-C4X-140211
| CAS No. | CATO-C4X-140211 |
| Molecular Formula | C12H10ClNO3 |
| Molecular Weight | 251.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Furosemide Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Furosemide Impurity 11 (CAS CATO-C4X-140211), a pharmacopoeial impurity reference standard (molecular formula C12H10ClNO3, MW 251.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Furosemide Impurity 11 (C12H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 251.67 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO3 |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Furosemide Standards
- Furosemide Impurity 12 (CAS 74793-12-7)
- Furosemide Impurity 59 (CAS 518336-22-6)
- Furosemide Impurity 50 (CAS 64174-54-5)
- Furosemide EP Impurity C (CAS 3086-91-7)
- Furosemide Impurity 64 (CAS 116436-17-0)
- Furosemide Impurity 51 (CAS CATO-C4X-140251)
- Furosemide Impurity 21 (CAS 30170-04-8)
- Furosemide Impurity 34 (CAS 6660-65-7)
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