Ibrutinib Impurity 98 CAS CATO-C4X-106498
| CAS No. | CATO-C4X-106498 |
| Molecular Formula | C8H14ClNO2 |
| Molecular Weight | 191.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ibrutinib Impurity 98 (C8H14ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 191.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Ibrutinib Impurity 98 (CAS CATO-C4X-106498, C8H14ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ibrutinib Impurity 98 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H14ClNO2 |
| Molecular Weight | 191.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ibrutinib Standards
- Ibrutinib Impurity N2 (CAS 43191-23-7)
- Ibrutinib Impurity N34 (CAS 98977-36-7)
- Ibrutinib Impurity 6 (CAS 143900-44-1)
- Ibrutinib Impurity 80 (CAS 109384-19-2)
- Ibrutinib Impurity N9 (CAS 86953-81-3)
- Ibrutinib Impurity 54 (CAS 1260862-85-8)
- Ibrutinib Impurity 193 (CAS 60034-89-1)
- Ibrutinib Impurity 156 (CAS 1642601-01-1)
Recommended Standards
- Milnacipran impurity 30 (CAS 115373-42-7)
- Trazodone Impurity 71 (CAS CATO-C4X-177271)
- 2955AF 6-Chloro-2-hydrazino-1,3-benzoxazole 912773-31-0 C7H6ClN3O (CAS 912773-31-0)
- 1-chloro-4-fluoro-isoquinoline (CAS 435278-06-1)
- Phloroglucinol impurity 47 (CAS CATO-C4X-221747)
- Ribavirin EP Impurity F (CAS 58151-87-4)
- Topiroxostat impurity 77 (CAS 103275-78-1)
- 7-Phenyl-pyrazolo[1,5-α]pyrimidine-2-carboxylic Acid (CAS 886503-17-9)
- (S)-3-Amino-4-(2,4-dimethoxyphenyl)butanoic acid (CAS 1253790-37-2)
- Propyl 2-chloroisonicotinate (CAS 898784-84-4)
- (R)-2-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethoxy)phenyl)propanoic acid (CAS 1213071-53-4)
- (4-Bromo-3-methylpyridin-2-yl)methanamine (CAS 886372-13-0)
- Methyl 5-azaspiro[2.3]Hexane-1-carboxylate hydrochloride (CAS 1375303-88-0)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com