Clonazepam impurity 7 CAS CATO-C4X-14037
| CAS No. | CATO-C4X-14037 |
| Molecular Formula | C15H9Cl3N2O4 |
| Molecular Weight | 387.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Clonazepam impurity 7 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Clonazepam impurity 7 (CAS CATO-C4X-14037) is a certified pharmaceutical impurity reference standard with the molecular formula C15H9Cl3N2O4 and a molecular weight of 387.60 g/mol.
The molecular framework of Clonazepam impurity 7 (C15H9Cl3N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clonazepam impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9Cl3N2O4 |
| Molecular Weight | 387.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Clonazepam Standards
- Clonazepam Impurity 4 (CAS 52130-87-7)
- Clonazepam Impurity 20 (CAS CATO-C4X-140320)
- Clonazepam Impurity 3 (CAS 180854-85-7)
- Clonazepam Impurity 23 (CAS CATO-C4X-140323)
- Clonazepam impurity 10 (CAS CATO-C4X-140310)
- Clonazepam impurity 11 (CAS CATO-C4X-140311)
- Clonazepam impurity 14 (CAS CATO-C4X-140314)
- Clonazepam Impurity 5 (CAS 17714-02-2)
Recommended Standards
- N-Butyroyl Phytosphingosine (CAS 409085-57-0)
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- N-(2-Chloro-4-iodophenyl)-4-methoxybenzamide (CAS 424807-10-3)
- (S)-4-(Methylthio)-2-palmitamidobutanoic acid (CAS 36416-81-6)
- Afatinib Impurity 64 (CAS CATO-C4X-100664)
- Rocuronium Impurity 26 (CAS CATO-C4X-124226)
- Dronedarone Impurity 56 (CAS 28141-24-4)
- Naphthalene-2,7-dicarbonyl dichloride (CAS 17989-82-1)
- 4-O-Methylsappanol (CAS 104778-16-7)
- 5-(Piperazin-1-ylsulfonyl)furan-2-carboxylic acid (CAS 1284925-88-7)
- Methyl 3-(3-formyl-1H-indol-1-yl)propanoate (CAS 1227954-70-2)
- 6-Chloro-2-methoxypyrimidine-4-carbaldehyde (CAS 2072804-90-9)
- 2-(1-Hydroxyethyl)-5-(2-hydroxyethyl)-3,4-dimethylthiazol-3-ium iodide (CAS 52084-19-2)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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