Megestrol Acetate EP Impurity I CAS CATO-C4X-14149
| CAS No. | CATO-C4X-14149 |
| Molecular Formula | C25H32O4 |
| Molecular Weight | 396.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Megestrol Acetate EP Impurity I is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Megestrol Acetate EP Impurity I (CAS CATO-C4X-14149, C25H32O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C25H32O4, Megestrol Acetate EP Impurity I contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 396.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Megestrol Acetate EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H32O4 |
| Molecular Weight | 396.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Megestrol Standards
- Megestrol acetate EP Impurity G (CAS 1259198-59-8)
- Megestrol acetate EP Impurity H (CAS 907193-65-1)
- Megestrol Acetate-d3 (CAS 162462-72-8)
- Megestrol Acetate EP Impurity J (CAS 14994-27-5)
- Megestrol Acetate EP Impurity C (CAS 74910-22-8)
- Megestrol Acetate EP Impurity D (CAS 32634-95-0)
- Megestrol-17-Acetate (CAS 595-33-5)
- Megestrol acetate (CAS 51154-23-5)
Recommended Standards
- Blonanserin Impurity 7 (CAS CATO-C4X-11107)
- Medroxyprogesterone impurity 8 (CAS 136803-81-1)
- Melengestrol Acetate Related Compound B (CAS 80097-73-0)
- Cyproterone Impurity 5 (CAS 30337-71-4)
- Bedaquiline Impurity 66 (CAS 1245907-31-6)
- Cinacalcet Impurity 64 (CAS CATO-C4X-105964)
- Brivaracetam Impurity 142 (CAS CATO-C4X-2007142)
- tert-Butyl (6-methoxybenzo[d]thiazol-2-yl)carbamate (CAS 1338645-97-8)
- Acenocoumarol Impurity 7 (CAS 10172-69-7)
- 2-Fluoro-5-methoxy-4-methylbenzoic acid (CAS 870221-15-1)
- 18:1 Phosphatidylmethanol (CAS 151379-99-6)
- 4-Amino-2-(diethylamino)pyrimidine-5-carbonitrile (CAS 93606-29-2)
- (8α,9<I>S</I>)-6′-methoxycinchonine-9-amine trihydrochloride (CAS 1231763-32-8)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
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