Megestrol acetate EP Impurity G CAS 1259198-59-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1259198-59-8
Molecular FormulaC25H34O4
Molecular Weight398.54 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Megestrol acetate EP Impurity G CAS 1259198-59-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Megestrol acetate EP Impurity G.

CATO supplies Megestrol acetate EP Impurity G (CAS 1259198-59-8), a pharmacopoeial impurity reference standard (molecular formula C25H34O4, MW 398.54 g/mol) used for the identification and quantification of trace impurities in APIs.

Megestrol acetate EP Impurity G (C25H34O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Megestrol acetate EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC25H34O4
Molecular Weight398.54 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990

Related Megestrol Standards

Recommended Standards

Why CATO?