Megestrol Acetate EP Impurity D CAS 32634-95-0
| CAS No. | 32634-95-0 |
| Molecular Formula | C24H32O4 |
| Molecular Weight | 384.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Megestrol Acetate EP Impurity D (CAS 32634-95-0) is a certified pharmaceutical impurity reference standard with the molecular formula C24H32O4 and a molecular weight of 384.51 g/mol.
The molecular framework of Megestrol Acetate EP Impurity D (C24H32O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Megestrol Acetate EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H32O4 |
| Molecular Weight | 384.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
Related Megestrol Standards
- Megestrol Acetate EP Impurity C (CAS 74910-22-8)
- Megestrol-17-Acetate (CAS 595-33-5)
- Megestrol acetate (CAS 51154-23-5)
- Megestrol Acetate EP Impurity J (CAS 14994-27-5)
- Megestrol Acetate EP Impurity E (CAS 982-89-8)
- Megestrol Acetate-d3 (CAS 162462-72-8)
- Megestrol Acetate EP Impurity I (CAS CATO-C4X-14149)
- Megestrol acetate EP Impurity G (CAS 1259198-59-8)
Recommended Standards
- Medroxyprogesterone Impurity 15 (CAS CATO-C4X-145715)
- Scillarenin (CAS 465-22-5)
- Medroxyprogesterone Impurity 16 (CAS CATO-C4X-145716)
- N-(4-Dodecanamidophenyl)furan-2-carboxamide (CAS 337505-74-5)
- Alfuzosin EP Impurity G (CAS 928780-95-4)
- Cefminox Impurity 41 (CAS CATO-C4X-192641)
- Arbidol Impurity 43 (CAS 40945-69-5)
- (1R,2R)-Cycloheptane-1,2-diol (CAS 108268-28-6)
- (S)-Ethyl 1-carbamothioyl-5-oxopyrrolidine-2-carboxylate (CAS 13591-07-6)
- Tert-butyl 2-(3-aminopiperidin-1-yl)acetate (CAS 1247796-36-6)
- 1-Methyl-3-(prop-2-yn-1-yl)urea (CAS 52829-73-9)
- 2-Hydroxy-3-propyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 94881-99-9)
- 3-Acetyl-5-chlorobenzonitrile (CAS 1393581-95-7)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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