Megestrol Acetate EP Impurity J CAS 14994-27-5
| CAS No. | 14994-27-5 |
| Molecular Formula | C24H34O4 |
| Molecular Weight | 386.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Megestrol Acetate EP Impurity J is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Megestrol Acetate EP Impurity J (CAS 14994-27-5, C24H34O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Megestrol Acetate EP Impurity J (C24H34O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Megestrol Acetate EP Impurity J under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H34O4 |
| Molecular Weight | 386.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Megestrol Standards
- Megestrol Acetate-d3 (CAS 162462-72-8)
- Megestrol Acetate EP Impurity C (CAS 74910-22-8)
- Megestrol Acetate EP Impurity D (CAS 32634-95-0)
- Megestrol-17-Acetate (CAS 595-33-5)
- Megestrol acetate (CAS 51154-23-5)
- Megestrol Acetate EP Impurity E (CAS 982-89-8)
- Megestrol Acetate EP Impurity I (CAS CATO-C4X-14149)
- Megestrol acetate EP Impurity G (CAS 1259198-59-8)
Recommended Standards
- Erythromycin impurity 75 (CAS 15797-36-1)
- Medroxyprogesterone Acetate EP Impurity D (CAS 2242-65-1)
- Ubiquinone Q3 (CAS 1173-76-8)
- Medroxyprogesterone Acetate (CAS 71-58-9)
- Roflumilast Impurity C65 (CAS 162401-60-7)
- Dotinurad Impurity 101 Oxalate (CAS 4433-52-7（free base ）)
- Adenosine Impurity 2 (CAS CATO-C4X-24192)
- 1-{2,7-diazaspiro[3.5]nonan-2-yl}ethan-1-one (CAS 1474026-47-5)
- (S)-2,6-Diamino-N-hydroxyhexanamide (CAS 25125-92-2)
- 2-(Aminomethyl)-6-chloro-4-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1805176-97-9)
- 8-Methoxy-3-phenyl-1,7-naphthyridin-2-yl trifluoromethanesulfonate (CAS 1632286-02-2)
- Aminoallyl-dUTP sodium salt (CAS 109921-28-0)
- (2-Bromo-3-(difluoromethyl)-4-fluorophenyl)methanol (CAS 2385292-41-9)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com