Desloratadine Impurity 65 CAS CATO-C4X-143065
| CAS No. | CATO-C4X-143065 |
| Molecular Formula | C19H18ClN3O2 |
| Molecular Weight | 355.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 355.82 g/mol gives Desloratadine Impurity 65 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Desloratadine Impurity 65 (CAS CATO-C4X-143065, C19H18ClN3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H18ClN3O2, Desloratadine Impurity 65 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 355.82 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18ClN3O2 |
| Molecular Weight | 355.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Desloratadine Standards
- Desloratadine Impurity 64 (CAS CATO-C4X-143064)
- Desloratadine Related Compound A (CAS 117796-50-6)
- Desloratadine impurity 66 (CAS CATO-C4X-143066)
- Desloratadine Impurity 28 (CAS CATO-C4X-143028)
- Desloratadine Impurity 9 (CAS 117796-52-8)
- Desloratadine Impurity 63 (CAS CATO-C4X-143063)
- Desloratadine Impurity 29 (CAS 79779-58-1)
- Iso Desloratadine Hydrochloride (CAS 432543-89-0)
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