Betamethasone Impurity 28 CAS CATO-C4X-143728
| CAS No. | CATO-C4X-143728 |
| Molecular Formula | C22H29O8P |
| Molecular Weight | 452.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Betamethasone Impurity 28 (CAS CATO-C4X-143728, C22H29O8P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Betamethasone Impurity 28 (C22H29O8P) contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.5, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 452.43 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Betamethasone Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H29O8P |
| Molecular Weight | 452.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Betamethasone Standards
- Betamethasone Impurity 111 (CAS CATO-C4X-1437111)
- Betamethasone Impurity 143 (CAS CATO-C4X-1437143)
- Betamethasone impurity 48 (CAS CATO-C4X-143748)
- Betamethasone Impurity 42 (CAS 25122-45-6)
- Betamethasone impurity 106 (CAS 330157-03-4)
- Betamethasone Impurity 108 (CAS CATO-C4X-1437108)
- Betamethasone 17-Propionate-d5 (CAS CATO-C4X-143735)
- Betamethasone impurity 66 (CAS 4735-64-2)
Recommended Standards
- tert-Butyl((5-iodopentyl)oxy)diphenylsilane (CAS 164025-54-1)
- Dexamethasone Impurity 129 (CAS CATO-C4X-1165129)
- Foramsulfuron (CAS 173159-57-4)
- 6-Acetyl-3-amino-N-(4-fluorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 727664-47-3)
- Besudil Impurity 14 (CAS CATO-C4X-298814)
- Mirabegron EP Impurity A (CAS 1796931-48-0)
- Desonide Impurity 11 (CAS 25092-32-4)
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- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com