Betamethasone impurity 74 CAS CATO-C4X-143774
| CAS No. | CATO-C4X-143774 |
| Molecular Formula | C22H28FO8P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 493.42 g/mol gives Betamethasone impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Betamethasone impurity 74 (CAS CATO-C4X-143774), a pharmacopoeial impurity reference standard (molecular formula C22H28FO8PNa, MW 493.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Betamethasone impurity 74 (C22H28FO8PNa) contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.5, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 493.42 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Betamethasone impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28FO8P 2*Na |
| Molecular Weight | 493.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
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- Betamethasone Dipropionate EP Impurity G (CAS 1186048-33-8)
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Recommended Standards
- Nicorandil impurity 68 (CAS CATO-C4X-190768)
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- 2-[[2-[[2-(Bis(Carboxymethyl)Amino)-5-Fluoro-4-Methylphenoxy]Methyl]Quinolin-8-Yl]-(Carboxymethyl)Amino]Acetic Acid (CAS 109024-53-5)
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- (5-Phenylpyrimidin-2-yl)methanol (CAS 126230-85-1)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com