Beclometasone Impurity 28 CAS CATO-C4X-147428
| CAS No. | CATO-C4X-147428 |
| Molecular Formula | C22H29ClO6 |
| Molecular Weight | 424.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Beclometasone Impurity 28 (C22H29ClO6) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Beclometasone Impurity 28 (CAS CATO-C4X-147428), a pharmacopoeial impurity reference standard (molecular formula C22H29ClO6, MW 424.92 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Beclometasone Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H29ClO6 |
| Molecular Weight | 424.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Beclometasone Standards
- Beclometasone Impurity 33 (CAS CATO-C4X-147433)
- Beclometasone Dipropionate Monohydrate EP Impurity U (CAS 79578-39-5)
- Beclometasone Dipropionate Monohydrate EP Impurity V (CAS 205105-83-5)
- Beclometasone Impurity 35 (CAS CATO-C4X-147435)
- Beclometasone Impurity 46 (CAS CATO-C4X-147446)
- Beclometasone Impurity 45 (CAS 34542-51-3)
- Beclometasone Impurity 47 (CAS CATO-C4X-147447)
- Beclometasone Impurity 44 (CAS 18769-20-5)
Recommended Standards
- Beclomethasone dipropionate Impurity 23 (CAS CATO-C4X-147423)
- Beclomethasone dipropionate Impurity 41 (CAS CATO-C4X-147441)
- Loratadine Impurity 65 (CAS CATO-C4X-142665)
- (+)-15(S)-Cloprostenol (CAS 54276-22-1)
- Imrecoxib Impurity 21 (CAS 1507299-93-5)
- Ceftazidime Impurity 48 (CAS 64513-00-4)
- Orniplabin Preparation and Separation of Impurity 2 (CAS CATO-CPS-2605002)
- Ethyl 5-(bis(2-hydroxyethyl)amino)-1H-indole-3-carboxylate (CAS 7150-82-5)
- 4,6-Diphenyl-2H-pyran-2-one (CAS 17372-52-0)
- N-(3-Chloro-4-methyl-phenyl)-succinamic acid ethyl ester (CAS 767327-45-7)
- tert-butyl (4-((3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propyl)(tert-butoxycarbonyl)amino)butyl)(3-aminopropyl)carbamate hydrochloride (CAS 1301739-22-9)
- 4-Methanehydrazonoylbenzene-1,2,3-triol (CAS 1865681-56-6)
- (2,4-Dichloropyridin-3-yl)(phenyl)methanone (CAS 134031-25-7)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com