Itraconazole Impurity 28 CAS CATO-C4X-149728
| CAS No. | CATO-C4X-149728 |
| Molecular Formula | C41H46Cl2N8O10 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Itraconazole Impurity 28.
As a process- or degradation-related impurity, Itraconazole Impurity 28 (CAS CATO-C4X-149728, C41H46Cl2N8O10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C41H46Cl2N8O10, Itraconazole Impurity 28 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 881.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Itraconazole Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C41H46Cl2N8O10 |
| Molecular Weight | 881.76 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Itraconazole Standards
- Itraconazole Impurity 44 (CAS 103661-14-9)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole 2-Oxo Metabolite (CAS 112560-33-5)
- Itraconazole Impurity 38 (CAS 115897-54-6)
- Itraconazole N-Formyl-Ethlene Impurity (CAS 1199350-00-9)
- Itraconazole Impurity 73 (CAS 1199350-02-1)
- Itraconazole-d5(major) (CAS 1217510-38-7)
Recommended Standards
- Levofloxacin Descarboxy Impurity（Levofloxacin EP Impurity E） (CAS 178964-53-9)
- Verteporfin Impurity 5 (CAS CATO-C4X-35495)
- Nitazoxanide impurity 01 (CAS 173903-47-4)
- 2-Bromo-4-methylbenzenesulfonamide (CAS 89694-63-3)
- 2-Allylbenzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 41335-56-2)
- 2-(2-(3-Bromobenzylidene)hydrazinyl)-N-(naphthalen-1-yl)-2-oxoacetamide (CAS 331264-78-9)
- Dimethylaluminum i-propoxide, 98% (99.99+%-Al) PURATREM (CAS 6063-89-4)
- 2556-53-8 Calcium dimethanolate Methanol, calcium salt (2:1) Methanol, calcium salt Calcium methylate EINECS 219-873-6 (CAS 2556-53-8)
- Terazosin-d8 (CAS 1006718-20-2)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com