Itraconazole Impurity 57 CAS CATO-C4X-149757
| CAS No. | CATO-C4X-149757 |
| Molecular Formula | C13H13Cl2N3O3 |
| Molecular Weight | 330.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Itraconazole Impurity 57.
Itraconazole Impurity 57 (CAS CATO-C4X-149757) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13Cl2N3O3 and a molecular weight of 330.17 g/mol.
Based on its molecular formula C13H13Cl2N3O3, Itraconazole Impurity 57 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 330.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Itraconazole Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13Cl2N3O3 |
| Molecular Weight | 330.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Itraconazole Standards
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole Impurity 95 (CAS CATO-C4X-149795)
- Itraconazole Impurity 23 (CAS 79538-90-2)
- Itraconazole Impurity 5 (CAS 74852-89-4)
- Itraconazole Impurity 18 (CAS 74853-07-9)
- Itraconazole Impurity 13 (CAS 308361-47-9)
- Itraconazole Impurity 25 (CAS 89848-19-1)
- Itraconazole Impurity 54 (CAS 170911-92-9)
Recommended Standards
- YE-120 (CAS 383124-82-1)
- N-(4-Bromophenyl)-4-fluorobenzenesulfonamide (CAS 727-32-2)
- Iprodione isomer 1 (CAS 63637-89-8)
- N-(4-Bromo-2-fluorophenyl)benzenesulfonamide (CAS 519017-71-1)
- Elagolix Impurity 102 (CAS CATO-C4X-2068102)
- Ertapenem Impurity 51 (CAS CATO-C4X-163351)
- Vericiguat impurity 50 (CAS CATO-C4X-289650)
- 1-Chloro-2-fluoro-5-nitronaphthalene (CAS 2757096-67-4)
- 6,7-Dimethyl-2-(pyridin-4-yl)indoline (CAS 591720-54-6)
- 4-Chloro-2-(phenylsulfanyl)-1,3-thiazole-5-carbaldehyde (CAS 199851-23-5)
- Darolutamide Impurity 29 (CAS CATO-C4X-310629)
- Aceclofenac Benzyl Ester (Aceclofenac EP Impurity F) (CAS 100499-89-6)
- 1,4-Benzenedicarboxylic acid, polymer with 5-methyl-1,9-nonanediamine (CAS 50507-31-8)
- SAMS Peptide (CAS 125911-68-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com