Norepinephrine Impurity 141 CAS CATO-C4X-1514141
| CAS No. | CATO-C4X-1514141 |
| Molecular Formula | C8H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Norepinephrine Impurity 141 (C8H11NO3C4H6O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Norepinephrine Impurity 141 (CAS CATO-C4X-1514141), a pharmacopoeial impurity reference standard (molecular formula C8H11NO3C4H6O6, MW 319.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11NO3 C4H6O6 |
| Molecular Weight | 319.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 50 (CAS 100622-09-1)
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 107 (CAS 112346-92-6)
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 161 (CAS 1215-29-8（free acid）)
Recommended Standards
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- 1-(2,3-Dihydrobenzofuran-5-yl)propan-1-amine (CAS 926231-02-9)
- 4-Bromo-2,3-difluorophenylacetonitrile (CAS 1627857-25-3)
- tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1407991-22-3)
- 3-Oxo-N,3-diphenyl-2-(phenylsulfonyl)propanamide (CAS 23064-33-7)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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