Cetirizine Impurity 33 CAS CATO-C4X-158233
| CAS No. | CATO-C4X-158233 |
| Molecular Formula | C19H22Cl2N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cetirizine Impurity 33 (C19H22Cl2N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 385.76 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Cetirizine Impurity 33 (CAS CATO-C4X-158233) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22Cl2N2HCl and a molecular weight of 385.76 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H22Cl2N2 HCl |
| Molecular Weight | 385.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cetirizine Standards
- Cetirizine EP Impurity B (CAS 1000690-91-4)
- Cetirizine Impurity 10 (CAS 1016-78-0)
- rac Cetirizine N-Oxide (Mixture of Diastereomers) (CAS 1076199-80-8)
- Cetirizine USP Related Compound B (CAS 108983-83-1)
- Cetirizine EP Impurity G (CAS 109806-71-5)
- (R)-Cetirizine-d4 Dihydrochloride (CAS 1133210-23-7)
- Cetirizine Impurity N19 (CAS 113740-61-7)
- rac Cetirizine-d8 N-Oxide (CAS 1216444-13-1)
Recommended Standards
- Apremilast Impurity 105 (CAS CATO-C4X-1009105)
- Brivaracetam Impurity 41 (CAS CATO-C4X-200741)
- Buspirone Impurity 39 HCl (CAS 80827-59-4(free base))
- 2-Propenoic acid, polymer with 1-propene (CAS 25214-24-8)
- 5-[(2-Butyloctyl)thio]-2-thiophenecarboxaldehyde (CAS 2316816-64-3)
- 2-Butoxy-1,3-dichloro-5-nitrobenzene (CAS 90919-96-3)
- 4-(5-Methyl-1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)butanoic acid (CAS 5554-91-6)
- 1-(2-(1H-Pyrrol-1-yl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate (CAS 55050-95-8)
- Morpholino(1-(6-(thiophen-2-yl)pyridazin-3-yl)piperidin-4-yl)methanone (CAS 1029761-45-2)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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