Safinamide Impurity 66 CAS CATO-C4X-159066
| CAS No. | CATO-C4X-159066 |
| Molecular Formula | C20H25FN4O3 |
| Molecular Weight | 388.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Safinamide Impurity 66 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Safinamide Impurity 66 (CAS CATO-C4X-159066), a pharmacopoeial impurity reference standard (molecular formula C20H25FN4O3, MW 388.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Safinamide Impurity 66 (C20H25FN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H25FN4O3 |
| Molecular Weight | 388.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Safinamide Standards
- Safinamide Impurity 60 (CAS CATO-C4X-159060)
- Safinamide Impurity 58 (CAS CATO-C4X-159058)
- Safinamide Impurity 65 (CAS CATO-C4X-159065)
- Safinamide Impurity 67 (CAS CATO-C4X-159067)
- Safinamide Impurity 37 (CAS 1000370-27-3)
- Safinamide Impurity 47 (CAS 1000370-28-4)
- Safinamide impurity 52 (CAS 100370-27-3)
- Safinamide Impurity 62 (CAS CATO-C4X-159062)
Recommended Standards
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
- Pioglitazone impurity 44 (CAS CATO-C4X-138344)
- Upadacitinib Impurity 197 (CAS CATO-C4X-2405197)
- Rabeprazole impurity 46 (CAS CATO-C4X-112146)
- Bosutinib Impurity 28 (CAS 65182-98-1)
- Amoxicillin impurity 111 (CAS CATO-C4X-1148111)
- Daprodustat impurity 5 (CAS CATO-C4X-24075)
- (6-Chloro-5-(difluoromethyl)-4-iodopyridin-3-yl)methanol (CAS 1806006-13-2)
- Formoterol EP Impurity A (Trifluoroacetic Acid) (CAS CATO-C4X-152533)
- 3-Amino-N-(2,4-difluorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-11-4)
- Ipconazole Impurity 2 (CAS 115937-89-8)
- 1-(4-Chlorobenzyl)-3-methyl-1H-pyrazole-5-carbohydrazide (CAS 618070-44-3)
- 2-(2-Fluoroethoxy)ethanol (CAS 373-22-8)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com