Dasatinib Impurity 4 CAS 910297-53-9
| CAS No. | 910297-53-9 |
| Molecular Formula | C22H24ClN7O3S |
| Molecular Weight | 501.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Dasatinib Impurity 4 (CAS 910297-53-9), a pharmacopoeial impurity reference standard (molecular formula C22H24ClN7O3S, MW 501.99 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dasatinib Impurity 4 (C22H24ClN7O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Dasatinib Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24ClN7O3S |
| Molecular Weight | 501.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 69 (CAS CATO-C4X-160769)
- Dasatinib Impurity 12 (CAS 910297-57-3)
- Dasatinib Impurity 15 (CAS 910297-58-4)
- Dasatinib Impurity 2 (CAS 910297-52-8)
- Dasatinib Impurity 47 (CAS CATO-C4X-160747)
- Dasatinib-d8 (CAS 1132093-70-9)
- Dasatinib impurity 63 (CAS CATO-C4X-160763)
- Dasatinib D4 (CAS 1160297-08-4)
Recommended Standards
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 573669-21-3)
- Benzyloxycarbonylglycyl-L-leucyl-L-phenylalanine chloromethyl ketone (CAS 41658-44-0)
- N-(2-Chloro-5-(trifluoromethyl)phenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-88-6)
- (Z)-4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-non-2-en-1-ol (CAS 261761-01-7)
- Melphalan EP Impurity J (CAS 2724549-95-3)
- Terbutaline Impurity 13 (CAS 13494-10-5)
- Opicapone impurity 61 (CAS CATO-C4X-240461)
- 1-Methyl-2-Pyrrolidone (CAS 872-50-4)
- 1,1'-Ethylenedipiperazine (CAS 19479-83-5)
- 1-(4-Nitrophenyl)piperidine-4-carboxamide (CAS 223786-49-0)
- 3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(Methyl Orthoacetate) (CAS 16697-49-7)
- 1-Methyl-2-(prop-1-en-2-yl)benzene (CAS 7399-49-7)
- Tiamulin impurity 19 (CAS CATO-C4X-221019)
- Anxiety Peptide (CAS 95237-86-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com