Fluticasone Propionate EP Impurity K CAS CATO-C4X-165044
| CAS No. | CATO-C4X-165044 |
| Molecular Formula | C25H31ClF2O5S |
| Molecular Weight | 517.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fluticasone Propionate EP Impurity K (C25H31ClF2O5S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Fluticasone Propionate EP Impurity K (CAS CATO-C4X-165044) is a certified pharmaceutical impurity reference standard with the molecular formula C25H31ClF2O5S and a molecular weight of 517.03 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fluticasone Propionate EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H31ClF2O5S |
| Molecular Weight | 517.03 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Propionate Chloro Analog (CAS 80486-69-7)
- Fluticasone Impurity 99 (CAS 948566-13-0)
- Fluticasone Impurity 64 (CAS CATO-C4X-165064)
- Fluticasone Propionate CP Impurity X (CAS 1648562-63-3)
- Fluticasone Furoate EP Impurity E (CAS 398454-97-2)
- Fluticasone Impurity 48 (CAS 397864-58-3)
- Fluticasone Impurity N6 (CAS 572880-17-2)
- Fluticasone Impurity 113 (CAS CATO-C4X-1650113)
Recommended Standards
- N-Nitroso Dasatinib (CAS CATO-C4X-160758)
- Dapagliflozin Impurity 116 (CAS CATO-C4X-1138116)
- Ethyl 1-[(4-chlorophenyl)methyl]-3-{[4-(2,5-dimethylphenyl)piperazin-1-yl]sulfonyl}-1H-pyrazole-4-carboxylate (CAS 1710202-77-9)
- Methyl 2-(2-(4-chloro-2-methylphenoxy)acetamido)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505096-47-9)
- Famciclovir Impurity 27 (CAS CATO-C4X-164227)
- Levocabastine impurity 16 (CAS CATO-C4X-228916)
- Doxapram EP Impurity B (CAS 1688-76-2)
- N-Boc-5-phenylpiperidine-3-carboxylic Acid (CAS 885274-99-7)
- 1-Octadecyl-4-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)pyridin-1-ium bromide (CAS 165678-32-0)
- Methyl 2-(3-butylpiperazin-1-yl)benzoate (CAS 1131622-72-4)
- Ethyl 2-(1-hydroxy-4-propylcyclohexyl)acetate (CAS 1248198-62-0)
- 4-Azidobutyric acid (CAS 54447-68-6)
- Biotinamidocaproate tobramycin amide, 98% (CAS 419573-19-6)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com