Irinotecan EP Impurity A HCl CAS CATO-C4X-166744
| CAS No. | CATO-C4X-166744 |
| Molecular Formula | C31H34N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Irinotecan EP Impurity A HCl.
CATO supplies Irinotecan EP Impurity A HCl (CAS CATO-C4X-166744), a pharmacopoeial impurity reference standard (molecular formula C31H34N4O6HCl, MW 595.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Irinotecan EP Impurity A HCl (C31H34N4O6HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 595.09 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Irinotecan EP Impurity A HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H34N4O6 HCl |
| Molecular Weight | 595.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Irinotecan Standards
- Irinotecan Hydrochloride (CAS 100286-90-6)
- Irinotecan Impurity 70 (CAS 100286-91-7)
- Irinotecan Impurity 69 (CAS 100286-92-8)
- Irinotecan Impurity 72 (CAS 100286-93-9)
- Irinotecan Impurity 71 (CAS 100286-94-0)
- Irinotecan Impurity N1 (CAS 1026078-50-1)
- Irinotecan EP Impurity A (CAS 103816-16-6)
- Irinotecan Impurity 14 (CAS 110351-94-5)
Recommended Standards
- Daprodustat impurity 7 (CAS CATO-C4X-24077)
- Bedaquiline Impurity 38 (CAS CATO-C4X-116738)
- Hydrocortisone Impurity 70 (CAS 116816-20-7)
- 2-(Difluoromethyl)-4-iodo-3-nitropyridine-6-sulfonyl chloride (CAS 1805546-39-7)
- 4-(Naphthalen-1-ylmethyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 642075-28-3)
- Methyl (4-chloro-5H-pyrrolo[3,2-d]pyrimidin-2-yl)carbamate, 97% (CAS 1598381-29-3)
- 7-Chloro-3,4-dihydro-3-oxo-4-(phenylmethyl)-2-quinoxalinepropanoic acid (CAS 568543-95-3)
- 2-chloro-1-(4,5-dihydrofuran-3-yl)-2,2-difluoroethan-1-one (CAS 1087784-77-7)
- 1-Cyclobutylcyclopropan-1-amine hydrochloride (CAS 1427379-90-5)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com