Abemaciclib impurity 119 CAS CATO-C4X-2937119
| CAS No. | CATO-C4X-2937119 |
| Molecular Formula | C42H44F4N12 |
| Molecular Weight | 792.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 792.87 g/mol gives Abemaciclib impurity 119 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Abemaciclib impurity 119 (CAS CATO-C4X-2937119, C42H44F4N12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Abemaciclib impurity 119 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 792.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abemaciclib impurity 119 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C42H44F4N12 |
| Molecular Weight | 792.87 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 12 |
Related Abemaciclib Standards
- Abemaciclib Impurity 144 (CAS CATO-C4X-2937144)
- Abemaciclib Impurity 46 (CAS CATO-C4X-293746)
- Abemaciclib Impurity 101 (CAS CATO-C4X-2937101)
- Abemaciclib Impurity 172 (CAS CATO-C4X-2937172)
- Abemaciclib Impurity 45 (CAS CATO-C4X-293745)
- Abemaciclib Impurity 48 (CAS CATO-C4X-293748)
- Abemaciclib Impurity 58 (CAS CATO-C4X-293758)
- Abemaciclib Impurity 179 (CAS CATO-C4X-2937179)
Recommended Standards
- Levothyroxine impurity 47 (CAS CATO-C4X-167847)
- Azlocillin Impurity 8 (CAS CATO-C4X-23208)
- Levothyroxine Impurity 30 (CAS 107849-54-7)
- CZBDF (CAS 1092578-51-2)
- Terbutaline impurity 100 (CAS CATO-C4X-1183100)
- Dapoxetine Impurity 18 (CAS 1091626-77-5)
- Levofloxacin impurity 72 (CAS CATO-C4X-137172)
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- (R)-1-(4-fluorophenyl)pentan-1-amine (CAS 239105-46-5)
- 3-Allyl-2-methylquinolin-4-amine (CAS 88322-58-1)
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- 4,4′-Bis(diphenylphosphinyl)-2,2′,6,6′-tetramethoxy-3,3′-bipyridine (CAS 220998-37-8)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com