Lidocaine Impurity 100 CAS CATO-C4X-1679100
| CAS No. | CATO-C4X-1679100 |
| Molecular Formula | C12H14Br2N2O2 |
| Molecular Weight | 378.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 378.06 g/mol gives Lidocaine Impurity 100 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Lidocaine Impurity 100 (CAS CATO-C4X-1679100, C12H14Br2N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lidocaine Impurity 100 (C12H14Br2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lidocaine Impurity 100 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14Br2N2O2 |
| Molecular Weight | 378.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Lidocaine Standards
- Lidocaine Impurity 74 (CAS CATO-C4X-167974)
- Lidocaine Impurity 92 (CAS CATO-C4X-167992)
- Lidocaine Impurity 72 (CAS CATO-C4X-167972)
- Lidocaine Impurity N4 (CAS 332903-68-1)
- Lidocaine impurity 58 (CAS CATO-C4X-167958)
- Lidocaine EP Impurity E (CAS 745798-07-6)
- Lidocaine Impurity 31 (CAS 70336-49-1)
- Lidocaine Impurity 81 (CAS CATO-C4X-167981)
Recommended Standards
- N-(2,5-dibromophenyl)-2-morpholinoacetamide (CAS 331460-39-0)
- 2,6-Bis(2,2,2-trifluoroethoxy)-3-bromobenzonitrile (CAS 175204-13-4)
- N-(2,4-dibromophenyl)-2-morpholinoacetamide (CAS 866154-43-0)
- (1R,2R)-1-iodo-2-(perfluoropropyl)cyclohexane (CAS 7589-43-7)
- Epirubicin Impurity 10 (CAS CATO-C4X-111610)
- Salbutamol Impurity 104 (CAS 27566-09-2)
- Cefminox Impurity 36 (CAS CATO-C4X-192636)
- methyl 4-oxo-3H,4H-pyrrolo[2,1-f][1,2,4]triazine-7-carboxylate (CAS 1909305-94-7)
- 1-(Difluoromethoxy)-3-iodonaphthalene (CAS 1261799-22-7)
- Benidipine Impurity 75 (CAS CATO-C4X-112075)
- 1-(1-Methyl-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-2-yl)piperidine-3-carboxylic acid (CAS 1707372-75-5)
- 5-Methylhexan-1-amine hydrochloride (CAS 1333628-05-9)
- 4-Phenylthieno[3,2-c]pyridine (CAS 81820-65-7)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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